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You might not need jQuery - http://youmightnotneedjquery.com/ 

Summary

# Selectors
<div id="lead">lorem ipsum</div>

<ul>
  <li class="blue">First item</li>
  <li class="red">Second item</li>
  <li class="blue">Third item</li>
  <li class="red">Last item</li>
</ul>
<p class="blue status">A great status</p>

// JQuery
var lead = $('#lead');
var firstRedItem = $('.red').eq(0);
var blueListItems = $('li.blue')

// ES6
const lead = document.getElementById('lead')
const firstRedItem = document.querySelector('.red')
const blueListItems = document.querySelectorAll('li.blue')

# Custom Selector Function
function $(selector, context) {
  var context = context || document
  var selectorType = 'querySelectorAll'
  var is_single_element = selector.indexOf('#') === 0

  if (is_single_element) {
    selectorType = 'getElementById'
    selector = selector.substr(1, selector.length)
  }

  var results = context[selectorType](selector)

  if (is_single_element) {
    return results
  } else {
    return [].slice.call(results)
  }
}

$('#lead')
$('input[type=text]')
$('textarea')

# Inserting into the DOM
<div id="comments">  
  <p class="comment">First!</p>
  <p class="comment">Enough with that!</p>
</div>

<form>  
  <textarea id="commentContent"></textarea>
  <button>Post comment</button>
</form>

// JQuery
var commentContent = $('#commentContent').val()
$('#comments').append('<p class="comment">' + commentContent + '</p>')

// ES6
const commentContent = document.getElementById('commentContent').value
const comments = document.getElementById('comments')
comments.insertAdjacentHTML('beforeend', `<p class="comment">${commentContent}</p>`)

# Modifying Classes
// JQuery
$(selector).addClass('bold');
$(selector).removeClass('bold');
$(selector).toggleClass('bold');

// ES6
// selected by getElementById or querySelector
element.classList.add('bold')
element.classList.remove('bold')
element.classList.toggle('bold')

// selected by querySelectorAll
elements.forEach((element) => {
  element.classList.add('bold')
})

# Event Listeners
<button id="btn">Click me!</button>

// With jQuery, we would use the .on() method (or one of its shortcuts):

$('#btn').on('click', function(event) {  
  alert('Thanks for clicking!');
});

// The modern DOM gives you addEventListener to play with:

const button = document.getElementById('btn');
button.addEventListener('click', (event) => {  
  alert('Thanks for clicking!');
});